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6-[(Cyanoethyl)thio]-7-deaza-dG (pac) CE-phosphoramidite
Modified Phosphoramidites , class 7-Deazapurine Nucleoside Phosphoramidites
6-[(Cyanoethyl)thio]-7-deaza-dG (pac) CE-phosphoramidite
Catalog # CBT-P-025
Compound 6-[(Cyanoethyl)thio]-7-deaza-dG (pac) CE-phosphoramidite
Chemical Name 4-[(2-Cyanoethyl)thio]-7-[2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosyl]-2-[(phenoxyacet)amino]-7H-pyrrolo[2,3-d]pyrimidine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Formula C52H58N7O8PS
Molecular Weight 972.10 g/mol
Properties Storage at -18°C

A new protocol for the covalent attachment of oligonucleotides to gold nanoparticles was developed using 6-thio-7-deaza-2-deoxyguanosine as molecular surface anchor. Compared to already existing conjugation protocols, the new linker strategy simplifies the synthesis of DNA gold nanoparticle conjugates. Incorporation of the sulfur-containing nucleosides can be performed at any position of an oligonucleotide; even multiple incorporations are feasible, which increases the binding stability of the corresponding oligonucleotides to the gold nanoparticles.
Appearance Off-white foam
References F. Seela, P. Ding, S. Budow, Bioconjugate Chem. 2011, 22, 794.
QuantityPricing (EUR)
50 µmol 180,00
100 µmol 320,00
250 mg 850,00
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