8-Aza-7-deaza-dA (ibu) CE-phosphoramidite
Modified Phosphoramidites , class 8-Aza-7-deazapurine Nucleoside Phosphoramidites
Catalog # |
CBT-P-090 |
Compound |
8-Aza-7-deaza-dA (ibu) CE-phosphoramidite |
Chemical Name |
1-[2-Deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosy]-4-(isobutyrylamino)-1H-pyrazolo[3,4-d]pyrimidine 3'-[(2-cyanoethyl)-N,N-diisopropyl-phosphoramidite] |
Formula |
C44H54N7O7P |
Molecular Weight |
823.92 g/mol |
Properties |
Storage at -18°C
Phosphoramidite building blocks of 8-aza-7-deaza-2'-deoxyadenosine were first reported in 1988. Oligonucleotide duplexes maintain their stability, when dA is replaced by 8-aza-7-deaza-dA residues. Furthermore, oligonucleotides containing this nucleoside cannot form Hoogsteen base pairs, thereby reducing mismatch formation. |
References |
F. Seela, K. Kaiser, Helv. Chim. Acta 1988, 71, 1813. |
Quantity | Pricing (EUR) |
50 µmol |
150,00 €
|
100 µmol |
280,00 €
|
250 mg |
650,00 €
|
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