Catalog # | CBT-P-025 |
Compound | 6-[(Cyanoethyl)thio]-7-deaza-dG (pac) CE-phosphoramidite |
Chemical Name | 4-[(2-Cyanoethyl)thio]-7-[2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosyl] -2-[(phenoxyacet)amino]-7H-pyrrolo[2,3-d]pyrimidine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
Formula | C52H58N7O8PS |
Molecular Weight | 972.10 g/mol |
Properties | Storage at -18°C A new protocol for the covalent attachment of oligonucleotides to gold nanoparticles was developed using 6-thio-7-deaza-2’-deoxyguanosine as molecular surface anchor. Compared to already existing conjugation protocols, the new linker strategy simplifies the synthesis of DNA gold nanoparticle conjugates. Incorporation of the sulfur-containing nucleosides can be performed at any position of an oligonucleotide; even multiple incorporations are feasible, which increases the binding stability of the corresponding oligonucleotides to the gold nanoparticles. |
Appearance | Off-white foam |
References | F. Seela, P. Ding, S. Budow, Bioconjugate Chem. 2011, 22, 794. |
Quantity | Pricing (EUR) |
50 µmol | |
100 µmol | |
250 mg |